2008年9月14日星期日
DNA paternity test
Identification of parent-child relations are the most use of DNA typing is identified. People's blood, hair, saliva, oral cells can be used by all paternity testing, is very convenient. A person has 23 pairs (46) chromosome, the same position on the same chromosome a gene called alleles, a general from his father and one from the mother. If a DNA test to the site of the allele, the same as a mother, father and another should be the same, otherwise there is a doubt. The use of DNA for paternity testing, as long as a few dozen to a dozen sites for DNA testing, if all the same, we can determine the parent-child relationship, if there are more than three different sites, parent-child relationship can be ruled out, there are 12-bit Different point, it should consider the possibility of gene mutations, and do some testing sites to identify. DNA paternity testing, the negative parent-child relationship of nearly 100 percent accuracy rate, certainly the accuracy of the parent-child relationship can be reached 99.99 percent. DNA paternity test test FAQ What is a DNA paternity test test » DNA (deoxyribonucleic acid) is the physical body of the atomic material. Each atom has 46 chromosomes, while men and women of the sperm cells and eggs, and each has 23 chromosomes, when the sperm and egg combination of time. This 46 atoms to create a life on the chromosome, each from a father who inherited half of the material elements, while the other half from the mother was. DNA paternity testing testing with the traditional blood tests are quite different. It can be in different tests on the samples, including blood, gills cavity cell, tissue samples and semen samples. Because blood type, such as Type A, B-, O-or-RH, the crowd in the use of more common, used to identify each individual's blood relationship, but as DNA paternity testing testing effective. In addition to the real twins, each person's DNA is unique. Because it is so unique, like fingerprints, for paternity testing, DNA is the most effective method. We are usually the result than the requirements of the court also accurate from 10 to 100 times.
DNA replacement
Gene therapy is integrated with the normal gene into the cells, to correction and replacement of a disease gene therapy. Currently in broad terms, some will be transferred to the genetic material of cells, in its role to achieve the objective method of treatment of disease, but also that of gene therapy. At present gene therapy, the method used can basically be divided into the following: 1 DNA Correction DNA correction that will be linked pathogenic DNA base pairs to correct the anomaly, and normal part be retained. 2. DNA replacement DNA replacement is to use the normal DNA in DNA by homologous recombination, in situ lesions replacement cells pathogen DNA, the DNA within the cell to fully return to normal conditions. 3. The addition of DNA DNA will be added to that purpose DNA into cells or other cell disease, removing abnormal DNA, but through DNA purpose of the non-targeting, the expression of compensation to the function of DNA defects or the original function has been strengthened. At present DNA for use of such methods. This approach is the addition of the more dominant DNA for the treatment of recessive disease. 4. DNA inactivation Early generally refers to anti-sense DNA technology. It is the specific anti-RNA, including antisense RNA, antisense and ribozymes DNA into cells, transcription and translation in blocking the abnormal expression of certain genes. In recent years another anti-gene strategy, peptide nucleic acid, DNA and RNA interference removal. [DNA is the genetic material of all biological basis: DNA (deoxyribonucleic acid) is a class of nucleic acid, the molecule contains deoxyribose named. DNA molecules very large (at least in general molecular weight over 1 million), the main component is deoxynucleotidyl adenine, guanine deoxynucleotidyl, thymine and cytosine deoxynucleotidyl deoxynucleotidyl. DNA exists in the nucleus, mitochondria, chloroplasts, can also be free to exist in some state of the cell cytoplasm. Most of the known phage, part of a small number of plant and animal virus also contain the virus in the DNA. In addition to RNA (ribonucleic acid) and the phage, DNA is the genetic material of all biological basis. Parent-child organisms and the similarity between the so-called inheritance of genetic information, are stored in the DNA molecule. 1953,詹姆斯沃森and Francis Crick describe the structure of DNA: from one-to-many linked nucleotide composition of each other coiled double helix. They and London's National Institute of Technology physicist Frederick Ke Wei Er Jinsi shared the 1962 Nobel Prize in Physiology or Medicine. [Obesity gene -- The Royal London Hospital scientists found that obesity in the body, there is a unique function of the gene, the gene of the three members of the body of the chromosome. As the obesity gene existed only in the body, so scientists call it "fat gene." The study found that obesity gene can promote the body to create a transport fat in the blood protein - "APO-D" gene. The gene, the more fat the more fluent of blood transmission, the accumulation of body fat also the more people will be obese. Below scientists did an interesting experiment: Let a pair of carrying the obesity gene mice mating, the results of each roll and future generations of wandering round melon, which is tantamount to meat ball, and did not allow a mouse obesity gene for mating, birth The less fat in mice, each are very thin. Genetic scientists in accordance with this model, can also produce the body of fat at 20 to 50 percent of the Feishou different degrees of mice. Further found that the genetic obesity and the situation is slightly different from rodents, a generational genetic. That is, people can observe, in a considerable number of families, fat grandmother would not normally be obese gene passed on to their children, but passed on to her grandchildren. Scientists also found that obesity-related genes more than one. For example, New York, a Rockefeller University research team recently announced that they After eight years of long study, found that a control appetite and energy metabolism genes. It is said that this gene can be sent to the brain to stop eating a signal to the brain so that the masters of timely weakening appetite, in order to avoid excess energy if the gene variation, the owner will be increased appetite, Tanzui eat, and eventually become A big fat man. Further research revealed that the gene from the 4500 base component, part of which can produce from 167 amino acids of the protein. If this normal protein synthesis, will be sent to the brain's signal to stop eating if the protein coding the amino acid composition of coding the first 105 amino acid residues of the unusual base, the signal will stop eating failure, leading to obesity.
dna
Deoxyribonucleic acid, or DNA, is a nucleic acid molecule that contains the genetic instructions used in the development and functioning of all known living organisms. The main role of DNA is the lon-term storage of information and it is often compared to a set of blueprints, since DNA contains the instructions needed to construct other components of cells, such as proteins and RNA molecules. The DNA segments that carry this genetic information are called genes, but other DNA sequences have structural purposes, or are involved in regulating the use of this genetic information
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