2008年9月12日星期五

Pleural mesothelioma

Pleural mesothelioma pleural mesothelioma for primary tumor, is derived from dirty layer, layer, or mediastinal pleura diaphragmatic four parts of the tumor. Foreign incidence rate higher than domestic, to 0.07 to 0.11 percent and 0.04 percent. All of the world's cancer mortality rate of 1 percent. In recent years, a clear upward trend. More than 50-year-old Most of male to female ratio was 2:1. With asbestos exposure. At present, the vicious type is still a lack of effective treatment methods. Clinical manifestations: 1. Localized may be no obvious discomfort or only chest pain, shortness of breath after the event. 2. Diffuse to a more severe chest pain, shortness of breath, weight loss, and so on. 3. Thorax side activities restricted, full, Kouzhenzhuoyin, breathing sound reduce or disappear. 4. Supraclavicular fossa have armpit and swollen lymph nodes. Diagnosis: 1. Chest pain, shortness of breath, weight loss and other symptoms. 2. Pleural thickening and pleural effusion signs. 3. Chest film or chest CT see pleural nodules shadow. 4. Thoracoscopy visible nodules, and clamp activities of the Organization for clear diagnosis. Treatment principles: Limitations of surgery should be the preferred treatment, can diffuse surgery and chemotherapy combination. Medication principles: 1. Chest pain who have used the skull-and anti-inflammatory pain, pethidine and other painkillers. 2. Adriamycin is an effective drug for the treatment of this disease, with more than cisplatin, mitomycin, cyclophosphamide, methotrexate, such as joint use. 3.γ-interferon, interleukin-as a complementary treatment. 4. Hydrothorax available to more than talc, such as tetracycline for pleural adhesions. Supplementary examination: Chest film and pleural effusion-based inspection of the screening examination. Conditional, as far as possible to do chest CT or MRI; Thoracoscopic from Huotizuzhi be confirmed. Evaluation: 1. Cure: symptoms and signs disappeared, mesothelioma disappeared or surgical excision. 2. Improved: symptoms, signs have improved significantly reduce the pleural effusion, mesothelioma narrow. 3.未愈: symptoms, no signs of improvement, hydrothorax increase speed, tumor

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